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In early stages of the disease, prostate cancer is limited to the prostate glands.
Approximately one third of patients with early stage prostate cancer will experience rising levels of prostate specific antigen, an indication that the disease is progressing.
In Stage 3, the prostate cancer has spread to nearby tissues and organs.
If the cancer spreads despite treatment to reduce male hormone levels, the disease is referred to as castration-resistant prostate cancer (CRPC). Approximately 80% of men with CRPC develop metastatic CRPC, a form of Stage 4 prostate cancer.
Stage 4 prostate cancer is the most advanced form of the disease.
The cancer has spread beyond the prostate to nearby organs and distant organs, such as lymph nodes or bone.
Prostate cancer is the second most frequently diagnosed cancer among men with 1 in 8 men likely to be diagnosed with prostate cancer in his lifetime. There are an estimated three million men living with prostate cancer in the U.S.