Science

2016

  • . Sintokamide A is a novel antagonist of androgen receptor that uniquely binds activation function-1 in its amino-terminal domain. JBC 2016

  • . An imaging agent to detect androgen receptor and its active splice variants in prostate cancer. JCI Insight 2016

  • . Androgen receptor targeted therapies in castration-resistant prostate cancer: Bench to clinic. International Journal of Urology 2016

  • . EPI-001, a compound active against castration-resistant prostate cancer, targets transactivation unit 5 of the androgen receptor. ACS Chem Biol 2016

  • . Analysis of AR-driven resistance mechanisms in a phase 1/2 study of EPI-506, a novel AR N-terminal domain inhibitor, in men with metastatic castration-resistant prostate cancer (mCRPC) with progression after enzalutamide or abiraterone. ASCO Annual Meeting 2016. (Abstract# TPS5030).